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KMID : 0939920020340060457
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대한암학회지
2002 Volume.34 No. 6 p.457 ~ p.460
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A Case of Primary Gastric Choriocarcinoma Presenting with Amenorrhea
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Seock Ah Im/Seung Hyun Nam
Seock Ah Im/Ki Sun Bae/In Sook Kang/Jung Mi Kwon/Kyung Eun Lee/Hye Sung Moon/Sun Hee Sung/Woon Sup Han/Chu Myong Seong/Soon Nam Lee
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Abstract
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Primary gastric choriocarcinomas are very rare, and their prognosis is extremely poor. A 37-year-old woman presented with amenorrhea, vaginal spotting and severe nausea, which mimicked a pregnancy and gestational trophoblastic disease. The serum level of the beta-subunit of human chorionic gonadotrophin (beta-hCG) was significantly increased. An endoscopic biopsy of the stomach mass showed the features of a choriocarcinoma, with marked anaplasia and necrosis. Immunohistochemical staining for beta-hCG showed positive results in the choriocarcinoma. Chemotherapy for the choriocarcinoma was administered, but she died 8 months following diagnosis.
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KEYWORD
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Choriocarcinoma, Stomach, Human chorionic gonadotrophin, Chemotherapy,
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